Medicine to prevent confusion after abdominal surgery in seniors
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial tests giving either lidocaine or dexmedetomidine during abdominal surgery to see if it helps keep the brain healthy and lowers the chance of waking up confused or agitated. It is for older adults having planned abdominal surgery who are otherwise in fairly good health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years old or older.
- You are scheduled for a planned (non-emergency) abdominal surgery.
- You have no serious memory or thinking problems, and you have not been diagnosed with a mental illness or a neurological condition.
- You are not taking any medications for the brain or nerves, such as those for seizures, Parkinson's, depression, or psychosis.
- You do not have severe kidney or liver disease.
- You are not allergic to lidocaine or dexmedetomidine, and you do not have a very slow heart rate or certain heart block conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at whether a medication called dexmedetomidine can reduce “postoperative delirium,” a temporary period of confusion after awake brain surgery. If you have the type of surgery the study focuses on, this could help your recovery and mental clarity afterward.
This study tests whether a combination of two medicines (dexmedetomidine and esketamine) and a gentle brain stimulation technique (tDCS) can help prevent confusion or memory problems that sometimes happen after surgery in older adults.
This study tests whether a medication called dexmedetomidine, given during or after hip fracture surgery, can help prevent confusion (delirium) that sometimes occurs in older patients after surgery. If you are 65 or older and having hip fracture surgery, this treatment might help you recover more clearly.
This study tests whether adding a medicine called dexmedetomidine to the spinal anesthesia can help prevent confusion (called delirium) after hip fracture surgery in older adults. It might help you recover more clearly and avoid post-surgery confusion.
This trial tests if a calming medicine (dexmedetomidine) given during and after brain tumor surgery can help prevent confusion or delirium afterwards.
This study tests whether using brain wave monitoring to guide pain medication during surgery can help older adults recover their thinking and memory faster after anesthesia. It might improve early mental recovery after a major operation.
Hear when a new Lidocaine trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.