Clin2
NCT07849517Possibly a fitNot yet recruiting

Pain control and confusion after knee replacement in older adults

Postoperative DeliriumPostoperative Pain, Acute

Part of Brain & nervous system, Mental health, Pain clinical trials.

This study looks at how different pain management methods after knee replacement surgery affect the risk of confusion (delirium) in older patients. It aims to find safer ways to manage pain and reduce confusion after surgery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
300 people
Ages
60 years and older
Study type
Interventional

Who can take part

  • You are having a planned (not emergency) knee replacement surgery on one knee.
  • You will be awake during surgery with numbing medicine in your spine (spinal anesthesia).
  • You are 60 years old or older.
  • Your body mass index (BMI) is between 18 and 30.
  • You do not have major memory or thinking problems, and you have not been taking certain strong pain or psychiatric medicines recently.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07432009Recruiting
Hip replacement and confusion risk in older adults

This study looks at whether older adults who get a hip replacement may experience confusion after surgery. It aims to find factors that might help prevent or reduce this confusion.

Brno
NCT06963294Not yet recruiting
Preventing confusion after hip or knee replacement surgery

This study tests two medicines (ketamine and dexmedetomidine) used during joint replacement surgery to see if they can prevent confusion (called delirium) that sometimes happens after surgery. Both medicines are commonly used in anesthesia, and the goal is to keep you mentally clear as you recover.

Istanbul, Merkez Mahallesi
NCT07235995Not yet recruiting· Phase 4
Painkiller and mannitol for confusion after surgery

This study tests whether giving a common painkiller (acetaminophen) combined with mannitol (a medicine that reduces swelling) can prevent or reduce confusion (delirium) after surgery. It is for older adults who are in the ICU with moderate to severe pain.

Changsha, Hunan
NCT06768580Recruiting
Melatonin or lidocaine to prevent confusion after hip replacement

This trial tests if giving either oral melatonin or lidocaine during surgery can reduce the chance of confusion (delirium) in older adults after total hip replacement. It compares these two approaches to standard care.

Tanta, El-Gharbia
NCT07810556Not yet recruiting· Phase 2/Phase 3
Adding a medicine to spinal anesthesia to prevent confusion after hip fracture surgery

This study tests whether adding a medicine called dexmedetomidine to the spinal anesthesia can help prevent confusion (called delirium) after hip fracture surgery in older adults. It might help you recover more clearly and avoid post-surgery confusion.

NCT07449468Recruiting
Nerve block to prevent confusion after hip replacement

This trial tests whether a nerve block (PENG block) can reduce confusion (delirium) after hip replacement surgery in older adults. It is for people 75+ scheduled for a first-time hip replacement under spinal anesthesia.

Poznan

Hear when a new Postoperative Delirium trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.