Clin2
NCT07603661Possibly a fitNot yet recruiting

Chemotherapy with immunotherapy for advanced lung cancer

Non Small Cell Lung Cancer

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a combination of an immunotherapy drug (sintilimab) with chemotherapy to shrink advanced lung cancer that cannot be removed with surgery. The goal is to see if the cancer becomes operable after treatment and to improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
33 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with non-small cell lung cancer that has not been treated yet.
  • The cancer is stage IIIC and cannot be removed with surgery.
  • You have not had prior treatment with immune checkpoint inhibitors or certain other cancer therapies.
  • You are willing to be re-evaluated for surgery and undergo surgery if the treatment makes it possible.
  • You are generally in good health with an ECOG performance status of 0 or 1.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07177105Not yet recruiting· Phase 2
Immunotherapy plus chemotherapy with surgery for advanced lung cancer

This trial tests whether giving a type of immunotherapy (sintilimab) along with chemotherapy before and after surgery to remove the main lung tumor can help people with advanced non-small cell lung cancer. The goal is to see if this approach improves outcomes compared to standard treatment.

NCT06883136Enrolling by invitation
Sintilimab plus chemo for elderly advanced lung cancer

This trial tests a combination of the immunotherapy drug sintilimab plus standard chemotherapy (platinum-based doublet) as the first treatment for older adults (60–80) with advanced non-small cell lung cancer that does not have certain gene mutations. The goal is to see if this approach works better than chemotherapy alone.

Jinan, Shandong
NCT06620822Not yet recruiting· Phase 2
Immunotherapy after surgery for lung cancer

This trial tests whether giving more immunotherapy after surgery can help people with non-small cell lung cancer who still had some cancer cells left after their first round of immunotherapy and chemotherapy before surgery. It aims to improve outcomes for those whose tumor didn't fully disappear.

Shanghai, Shanghai Municipality
NCT05429463Recruiting· Phase 3
Surgery-ready lung cancer treatment with immunotherapy plus chemo

This trial studies adding an immunotherapy drug (sintilimab) to standard chemotherapy before surgery for resectable squamous non-small cell lung cancer. It aims to shrink the tumor and improve outcomes, while still keeping the cancer operable.

Hangzhou, Zhejiang
NCT07410975Recruiting· Phase 2
Immunotherapy and chemo before surgery for lung cancer

This trial tests combining two immunotherapy drugs (anti-CTLA-4 antibody and sintilimab) with chemotherapy before surgery for stage II-III non-small cell lung cancer. The goal is to see if this approach helps shrink tumors and improve outcomes.

Shanghai, Shanghai Municipality
NCT06962189Not yet recruiting· Phase 2
Immunotherapy and chemo before surgery for advanced lung cancer

This study tests a combination of an immunotherapy drug (sintilimab) and chemotherapy to see if it can shrink advanced lung cancer enough to make surgery possible. The goal is to improve outcomes for people whose cancer is currently too extensive for surgery.

Hear when a new Non Small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.