Vaccine Study for Lynch Syndrome Prevention
Part of Cancer, Digestive system, Genetic & congenital, Hormones & metabolism clinical trials.
This study tests whether a new vaccine made from dendritic cells (immune cells) can help prevent cancer in people with Lynch syndrome, a genetic condition that increases cancer risk. The vaccine is designed to train your immune system to catch and destroy precancerous cells before they become cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed genetic mutation in MLH1, MSH2, or MSH6 (the genes that cause Lynch syndrome)
- You are between 35–75 years old (age 40–75 if MSH6 mutation)
- You have not had a total or near-total colon removal surgery
- You had a colonoscopy within the past 4 months showing no signs of cancer
- Your blood counts and kidney/liver function are healthy enough for the study
- You are willing to use birth control for up to 8 weeks after treatment if you can become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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