Clin2
NCT07612774Likely a fitRecruiting

Early cholesterol-lowering drug after heart attack study

CoronaryCoronary Artery Disease

Treatments studied

Part of Heart & circulation clinical trials.

This study tests whether starting evolocumab (a cholesterol-lowering injection) soon after a heart attack helps prevent future heart problems. You'll receive the study drug or placebo for 52 weeks while your heart is monitored with imaging scans.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
232 people
Ages
40 years to 75 years
Study type
Interventional

Who can take part

  • Had a heart attack (STEMI, NSTEMI, or unstable angina) treated with stent placement in the last week
  • Age 40–75 years
  • High cholesterol (LDL-C) that isn't well controlled by statins alone
  • Willing to have heart imaging scans and blood tests at the start and follow-up visits
  • Able to commit to 52 weeks of follow-up care and study visits
  • No previous heart surgery, bypass, or prior stent placements

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07803679Not yet recruiting· Phase 4
Evolocumab to shrink plaque in early heart disease

This study tests whether evolocumab, a monthly injection, can shrink the fatty buildup (plaque) in your heart arteries. It is for people who have early signs of heart disease or diabetes but have not had a heart attack or stroke yet.

NCT07799779Not yet recruiting· Phase 4
Early cholesterol treatment for heart attack patients

This study tests whether a newer cholesterol-lowering injection, given early after a heart attack, helps keep the plaque in your arteries stable and reduces future risk. It compares the new medicine added to your usual statin treatment.

Seongnam-si, Gyeonggi-do
NCT06854523Not yet recruiting
Early cholesterol-lowering treatment after a heart attack

This study tests whether starting a cholesterol-lowering injection (a PCSK9 inhibitor) early after a heart attack can slow or shrink the buildup of plaque in other heart arteries that are not the one that was stented. If you have two other arteries with mild blockages, this treatment might help prevent future heart problems.

Beijing, Beijing Municipality
NCT05152888Recruiting· Phase 4
Testing a cholesterol drug to improve heart blood flow on scans

This trial studies whether lowering LDL (“bad cholesterol”) with a PCSK-9 inhibitor (evolocumab) improves blood flow to the heart, measured by special PET scans. It’s for people over a certain age who have stable coronary artery disease and a higher risk of heart problems.

Boston, Massachusetts
NCT07208006Recruiting
Early cholesterol-lowering drug after heart attack

This trial tests whether giving a powerful cholesterol-lowering drug (PCSK9 inhibitor) very early after a heart attack can help prevent further heart problems. It is for people who have had a recent heart attack and have blockages in more than one heart artery.

Shanghai, Shanghai Municipality
NCT05587621Not yet recruiting
Intensive cholesterol-lowering after a heart attack

This study tests whether giving a strong cholesterol-lowering treatment right after a heart attack helps reduce the chance of future heart problems. It's for people who are not already on cholesterol medications.

Jena, Thuringia

Hear when a new Coronary artery disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.