Azithromycin for preventing heart damage in rheumatic heart disease
Treatments studied
Part of Bones, joints & muscles, Heart & circulation, Infections, Skin clinical trials.
This study tests whether the antibiotic azithromycin can help prevent further heart damage in young people with mild or moderate rheumatic heart disease (a condition caused by rheumatic fever that affects the heart valves). Participants will receive study medication and regular check-ups to see if it helps keep their heart healthy.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 10 and 18 years old.
- You must have a confirmed diagnosis of mild or moderate rheumatic heart disease (a heart condition caused by rheumatic fever).
- You must be able to attend monthly check-ups at one of the study sites, or you may be screened at school as part of the study.
- You must be willing to follow the study schedule and, if you are a girl who could become pregnant, agree to avoid pregnancy during the trial.
- You cannot be allergic to penicillin or have had a severe allergic reaction to antibiotics in the past.
- You must not be pregnant or breastfeeding, and you must not have any other serious health conditions that could make the study unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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