Safely Reducing Heart Failure Medications After Recovery
Part of Heart & circulation clinical trials.
This study tests whether patients whose heart function has fully recovered after surgery or a heart procedure can safely reduce or stop their heart failure medications. Researchers will carefully monitor whether gradually lowering these medicines is safe and maintains heart health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 19 or older
- Previously had weak heart function (ejection fraction ≤40%) that improved to normal (≥50%) after surgery or procedure
- Currently taking two specific heart failure medications (ARNI and SGLT2i) for at least 3 months
- Heart failure was caused by a correctable problem like valve disease or blocked arteries—not an ongoing genetic or idiopathic condition
- No heart failure hospitalizations in the past 6 months and clinically stable
- Blood markers (NT-proBNP) in a normal range and kidney function adequate (eGFR ≥30)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether it is safe to slowly reduce some heart failure medications for people whose heart function has improved to normal. It is for patients who once had a weak heart pump but now have recovered strength and are stable on multiple medicines.
This study tests whether starting two heart failure medications later, after a procedure to fix the heart's problem, is safe and helpful. It aims to see if waiting a bit can still improve heart function and quality of life.
This study tests whether patients whose heart failure has improved can safely reduce some of their medications. If your heart function has recovered significantly and stayed stable, this trial explores whether you can gradually lower doses of heart failure drugs while staying healthy.
This trial is testing whether people whose heart failure has improved (with better pumping strength) can safely stop taking some of their heart medications. It is for stable patients who have had significant improvement in their heart function from a low point.
This trial tests whether people whose heart function has returned to normal after heart failure can safely stop taking beta-blockers. It aims to see if staying on the medication is still needed or if stopping is just as safe.
This trial tests if patients whose heart function returned to normal after treating a fast heartbeat can safely stop their heart failure medications. It aims to see if treatment can be withdrawn without the heart problems coming back.
Hear when a new Heart Failure With Reduced Ejection Fraction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.