Reducing Heart Failure Meds After Heart Recovery Study
Part of Heart & circulation clinical trials.
This trial tests whether it is safe to slowly reduce some heart failure medications for people whose heart function has improved to normal. It is for patients who once had a weak heart pump but now have recovered strength and are stable on multiple medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your heart function (ejection fraction) was once below 40% but has now improved to 50% or higher.
- You must be on at least three heart failure medications (like ACE inhibitors, beta blockers, or spironolactone).
- Your NT-proBNP level (a blood test for heart stress) needs to be within a safe range adjusted for your kidney health.
- You cannot have high blood pressure that is not controlled (over 150/90).
- You cannot have had a heart procedure (like a stent or bypass) in the last 6 months, or have significant valve disease or an irregular heartbeat needing treatment.
- You cannot be pregnant or have kidney disease with protein in your urine.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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