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NCT06128980Possibly a fitRecruiting

Stopping heart meds after recovery from fast heartbeat damage

Heart Failure With Reduced Ejection FractionHeart Rhythm Disorder

Treatments studied

Part of Heart & circulation, Hormones & metabolism clinical trials.

This trial tests if patients whose heart function returned to normal after treating a fast heartbeat can safely stop their heart failure medications. It aims to see if treatment can be withdrawn without the heart problems coming back.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
348 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have new heart failure with a weak heart pump (ejection fraction 40% or less) and symptoms like shortness of breath or fatigue (NYHA class 2 or higher).
  • You have atrial fibrillation or flutter with a heart rate of 110 beats per minute or faster.
  • After treating the fast heartbeat (e.g., with ablation or medication), your heart function improved: ejection fraction is now 50% or more, your heart size normalized, your ECG is normal, and a blood test (NT-proBNP) is below 250 pg/ml.
  • You are 18 or older and can give consent.
  • You do not have significant heart valve disease, inherited heart muscle disease, or other serious heart conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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