Clin2
NCT07645326Possibly a fitNot yet recruiting

Risk-adapted treatment for metastatic prostate cancer

Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Treatments studied

Part of Cancer, Hormones & metabolism clinical trials.

This trial looks at whether treatment for metastatic prostate cancer can be tailored to each patient's risk level, potentially using less intensive therapy for lower-risk disease. It aims to maintain effectiveness while reducing side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
108 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have prostate cancer that has spread to other parts of the body and has not been treated with hormone therapy before.
  • You have not had chemotherapy (other than docetaxel) for prostate cancer in the past.
  • You have not received radiation therapy within the last 2 weeks.
  • You have not taken certain hormone therapy pills for non-metastatic prostate cancer within the last 6 months.
  • You can swallow oral medications and are willing to follow the treatment plan.
  • You do not have leptomeningeal disease (cancer spread to the membranes around the brain and spinal cord).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05649943Recruiting
New prostate cancer treatment plus local therapy for metastatic cases

This trial studies whether adding apalutamide to standard hormone therapy (ADT) improves outcomes for men with metastatic hormone-sensitive prostate cancer. Some people may also receive local treatments (like surgery or radiotherapy) to control the prostate and nearby areas.

Milan, Lombardy
NCT03903835Recruiting· Phase 3
Biomarker-guided treatment for metastatic prostate cancer

This Phase 3 trial tests a prostate cancer treatment plan chosen using your tumor’s biomarker results. It aims to improve outcomes for men with metastatic prostate cancer starting first systemic treatment.

Aalst
NCT07649421Not yet recruiting· Phase 2
Targeted radiation plus darolutamide for prostate cancer that has spread

This trial tests a combination of precise radiation therapy (SBRT) and a drug called darolutamide for men whose prostate cancer has spread to a limited number of other parts of the body. The goal is to see if this approach can control the cancer effectively with fewer side effects.

Chengdu, Sichuan
NCT07711002Recruiting· Phase 3
Saruparib with standard therapy for metastatic hormone-sensitive prostate cancer

This trial tests a new drug called saruparib, which may help keep prostate cancer from growing. It is for men whose cancer has spread and who have already received certain treatments. The study combines saruparib with a standard hormone therapy to see if it works better than the hormone therapy alone.

Hot Springs, Arkansas
NCT07216248Recruiting· Phase 2
Smart monitoring for men with advanced prostate cancer

This study tests if a smartphone-based tracking system can help doctors decide when to change treatment for men with hormone-sensitive prostate cancer that has spread. It uses standard drugs (relugolix and an ARPI) and monitors PSA levels closely.

Salt Lake City, Utah
NCT07190300Recruiting· Phase 1/Phase 2
Study of tulmimetostat plus other hormone therapies for metastatic prostate cancer

This study tests two different combinations of drugs for men with prostate cancer that has spread to other parts of the body but still responds to hormone therapy. It compares a new pill (tulmimetostat) combined with standard treatments like darolutamide or abiraterone to see if it can help control the cancer longer.

Birmingham, Alabama

Hear when a new Metastatic Hormone-sensitive Prostate Cancer (mHSPC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.