Chemotherapy plus double immunotherapy before surgery for sinonasal cancer
Treatments studied
Part of Cancer, Ear, nose & throat clinical trials.
This trial tests a combination of chemotherapy (docetaxel and cisplatin) plus two immunotherapy drugs before surgery for people with newly diagnosed, locally advanced sinonasal cancer. The goal is to see if this combination helps shrink the tumor and improves the chance of successful surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 75 years old.
- You must have been recently diagnosed with sinonasal cancer that is locally advanced (stage III or IVA).
- You must be in good enough health to walk and take care of yourself (a performance status score of 0 or 1).
- You must not have had prior immunotherapy (like PD-1 or PD-L1 inhibitors).
- You must not have an active autoimmune disease or need long-term steroids.
- You must be willing to use effective birth control during the study and for 3 months after treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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