Melatonin and magnesium sulfate vs. magnesium alone for HIE
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests whether adding melatonin to standard magnesium sulfate treatment improves outcomes for newborns with HIE (a brain injury from lack of oxygen). It compares the combination to magnesium sulfate alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby was born at full term (37 weeks or later).
- Your baby had a low Apgar score (less than 5) at 1 minute after birth.
- Cord blood test showed acidosis (low pH or high base deficit).
- Your baby has been diagnosed with at least moderate hypoxic-ischemic encephalopathy (HIE).
- Your baby does not have major birth defects, growth restriction, suspected infection, heart disease, or inherited metabolic disorders.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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