Using a fluorescent dye to guide surgery for focal cortical dysplasia
Treatments studied
Part of Brain & nervous system, Genetic & congenital clinical trials.
This study tests whether using a special fluorescent dye to highlight the abnormal brain tissue during surgery can help surgeons remove it more completely. This may improve seizure control for people with a specific type of epilepsy caused by a brain abnormality called focal cortical dysplasia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have epilepsy that hasn't been controlled by at least two different seizure medicines.
- Your MRI shows a type of brain abnormality called focal cortical dysplasia (FCD) type II, and your doctors have recommended surgery to remove it.
- This would be your first surgery for this brain abnormality.
- You must be able to have an MRI without general anesthesia (so no severe claustrophobia, obesity that prevents scanning, or unsafe metal implants).
- You must weigh less than 75 kg (about 165 pounds).
- You are not pregnant or breastfeeding (if you could become pregnant) and agree to use contraception during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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