Drug combination to avoid bladder removal in muscle-invasive bladder cancer
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This trial tests a combination of two drugs (enfortumab vedotin and pembrolizumab) to see if it can help people with muscle-invasive bladder cancer avoid bladder removal surgery. The goal is to preserve the bladder while still treating the cancer effectively.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with muscle-invasive bladder cancer (urothelial type) that has not spread beyond the bladder area.
- You are looking for a treatment option that may help you avoid bladder removal surgery, or you are not healthy enough for surgery.
- You have a tissue sample (biopsy) from your bladder tumor available for testing.
- You are generally able to care for yourself (ECOG performance status 0 or 1).
- You have not had prior radiation to the pelvic area or prior IV treatment for bladder cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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