Left bundle pacing plus CRT vs. LBBP alone
Part of Heart & circulation clinical trials.
This trial tests a new pacing approach that combines a left bundle branch pacemaker with standard cardiac resynchronization therapy (CRT) for people with heart failure. It aims to improve the heart's pumping efficiency compared to using the left bundle branch pacemaker alone.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have heart failure with a weak pump (ejection fraction 50% or less), a wide electrical pattern on EKG (QRS of 130 ms or more), and you are not in a fast, uncontrolled irregular rhythm.
- You have moderate to severe heart failure symptoms (NYHA class II-IV).
- Your heart veins can accept a standard pacing wire placed through the coronary sinus.
- You do not need a defibrillator (ICD) and you are not scheduled for major heart surgery during the trial.
- Your overall health allows you to live at least a year and you can follow the study schedule.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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