New ECG method to predict CRT benefit in heart failure
Part of Heart & circulation clinical trials.
This trial tests a new way to use an ECG (electrical heart recording) to predict who will benefit from a special pacemaker called cardiac resynchronization therapy (CRT). It is for people with heart failure and a specific heart rhythm problem.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have heart failure from blocked arteries or other heart muscle disease.
- You have symptoms like shortness of breath or fatigue with activity or at rest (NYHA class II to IV).
- Your heart's pumping strength (left ventricle ejection fraction) is 40% or less.
- An ECG shows your heart's electrical signal is wider than 130 milliseconds (wide QRS).
- You have a specific type of electrical block called 'left bundle branch block' (LBBB), confirmed by a special heart test.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
This trial tests a special pacing method for people with heart failure. It aims to improve the heart's pumping by using a more natural pacing approach.
This trial tests a noninvasive way to map your heart’s wiring and veins to help guide placement of a heart resynchronization therapy (CRT) device. If you have certain abnormal heart rhythm and weak heart pumping, it may help doctors place the therapy more accurately and safely.
This trial looks at how well an echocardiogram (ultrasound of the heart) can predict outcomes for people with left bundle branch block who already have cardiac resynchronisation therapy (CRT). If you qualify, your heart scans may be used to better estimate risk and guide care.
This trial tests a new pacing approach that combines a left bundle branch pacemaker with standard cardiac resynchronization therapy (CRT) for people with heart failure. It aims to improve the heart's pumping efficiency compared to using the left bundle branch pacemaker alone.
This trial tests a pacing approach designed to improve how the heart beats in some people with heart failure and a specific heart rhythm pattern on ECG. If you already need a device (CRT-D) based on your results, the study may help see whether this pacing correction improves outcomes.
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