Testing a new heart pacing method for CRT nonresponders
Part of Heart & circulation clinical trials.
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can sign consent and follow study visits and instructions.
- You are 18 to 80 years old.
- You have heart failure symptoms for at least 3 months, and symptoms are not mild (NYHA class II or higher).
- You have a heart muscle weakness condition (ischemic or non-ischemic cardiomyopathy) and reduced pumping strength.
- You previously tried biventricular CRT but did not respond, despite CRT-D (or CRT-D lead replacement) being done at least 1 year ago.
- Your current heart failure medicines are already optimized as best your doctors can.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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