Clot-dissolving medication for stroke caused by medium vessel blockage
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether giving clot-dissolving medication directly into the blocked brain artery (intra-arterial thrombolysis) improves recovery from acute stroke caused by a medium-sized vessel blockage. It aims to see if this treatment helps patients regain function better than standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 80 years old.
- Treatment must start within 24 hours of when your stroke symptoms began.
- You must have a stroke caused by a blockage in a medium-sized blood vessel in the brain, confirmed by imaging.
- Before the stroke, you were able to walk and take care of yourself (you had little or no disability).
- You cannot have certain bleeding risks, severe health conditions, or be pregnant or breastfeeding, among other safety checks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new clot-busting medicine called tenecteplase, given directly into the blood vessel in the brain, to treat strokes caused by a blockage in a medium-sized artery. The goal is to see if it can help restore blood flow and reduce disability, especially for patients who can be treated within 24 hours of stroke onset.
This trial tests a clot-busting drug given directly into the arteries of the brain for people who have had a stroke due to a blockage in a medium-sized artery. It aims to see if this treatment can help improve recovery when started up to 72 hours after symptoms begin.
This trial tests a clot-busting drug called tenecteplase given directly into the brain artery for people having a moderate stroke caused by a blockage in a medium-sized blood vessel. The goal is to see if it helps improve recovery when given within 24 hours of stroke symptoms starting.
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This trial tests whether giving a clot-busting drug to people with mild stroke symptoms (but no limb weakness) can improve recovery. It aims to see if this treatment is safe and helpful for this specific group.
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