Intra-arterial clot-busting drug for medium artery stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests a drug injected directly into the blocked brain artery through a catheter (intra-arterial thrombolysis) to treat acute strokes caused by medium-sized vessel blockages. It may help reopen the vessel faster and reduce disability, even if you arrive up to 24 hours after symptoms began.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 80 years old.
- The stroke must have started within the last 24 hours.
- You must have a moderate to severe stroke (NIHSS score 6 or higher, or 3-5 with disabling symptoms like weakness or trouble speaking).
- The blockage must be in a medium-sized brain artery (like M2/M3, A2/A3, or P1/P2/P3) and only one blocked vessel.
- You must not have had a recent seizure when the stroke started, and you must be able to safely undergo a catheter-based procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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