Clot-busting medicine for stroke symptoms 4.5 to 24 hours
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests a clot-busting medicine given through an IV to people who had a stroke caused by a blocked medium-sized blood vessel in the brain, and who can be treated 4.5 to 24 hours after symptoms start. The goal is to see if it improves recovery and reduces disability compared to standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Before this stroke, you could live independently (no significant disability).
- Your stroke symptoms started between 4.5 and 24 hours ago, or you woke up with them.
- A CT or MRI scan shows a blocked blood vessel in a medium-sized artery in your brain.
- You have not already had clot-busting medicine or a clot-removal procedure for this stroke.
- You are not at high risk of bleeding, and do not have certain other serious health conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a clot-dissolving medication given within 4.5 hours of a stroke caused by a blocked blood vessel. The goal is to see how well it works in real-world patients and to help improve recovery.
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This trial tests giving a second dose of an IV clot-dissolving medicine (prourokinase) to patients who had a stroke from a large clot but didn't improve enough after the first dose. The goal is to see if a second dose within 6 hours of stroke onset can help more patients recover.
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