New diabetes pill vs. injected medicine in teens with type 2 diabetes
Treatments studied
Part of Hormones & metabolism clinical trials.
This study tests a new daily pill, orforglipron, compared to another injectable medicine (dulaglutide) in children and teens with type 2 diabetes. It aims to see if the new pill can improve blood sugar control with fewer injections.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have type 2 diabetes and are currently managing it with diet, exercise, and metformin and/or a long-acting insulin.
- Your most recent A1C (average blood sugar over 2-3 months) is between 6.5% and 11.0%.
- You weigh at least 110 pounds (50 kg) and have a BMI above the 85th percentile for your age and sex.
- You have not had diabetic ketoacidosis or severe low blood sugar episodes in the past 6 months.
- You have never had pancreatitis, gallbladder disease, or a family history of a rare thyroid cancer called MTC or MEN2.
- You have not taken any other diabetes pills or weight-loss medications in the last 90 days besides metformin, long-acting insulin, or SGLT2 inhibitors.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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