Study of two diabetes medicines for teens and children
Treatments studied
Part of Hormones & metabolism clinical trials.
This study tests an experimental daily pill (orforglipron) against an approved weekly injection (dulaglutide) in young people with type 2 diabetes. It aims to see which works better at controlling blood sugar and may offer a more convenient option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have type 2 diabetes and are currently managing it with diet, exercise, and either metformin or basal insulin (or both).
- Your most recent A1C blood sugar test is between 6.5% and 11.0%.
- You weigh at least 110 pounds (50 kilograms) and your body mass index (BMI) is above the 85th percentile for your age and gender.
- You do not have type 1 diabetes.
- You have not had diabetic ketoacidosis or hyperosmolar syndrome since your type 2 diabetes diagnosis.
- You have not had severe low blood sugar or unawareness of low blood sugar in the last 6 months.
- You have no history of pancreatitis or gallbladder disease.
- You and your family have no history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2.
- You have not used any other diabetes medicines (besides metformin, basal insulin, or SGLT2 inhibitors) in the last 90 days.
- You have not used any prescription or over-the-counter weight-loss medications in the last 90 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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