Clin2
NCT07670312Possibly a fitNot yet recruiting

Testing XYA02 for advanced solid tumors

MUC1-expressing Advanced, Relapsed and/or Refractory Solid TumorsNon-Small Cell Lung CancerOvarian CancerGEJ AdenocarcinomaColorectal CancerPancreatic Adenocarcinoma

Part of Cancer, Digestive system, Hormones & metabolism, Lungs & breathing, Women’s health & pregnancy clinical trials.

This study tests an experimental drug called XYA02 for people with advanced solid tumors (like lung, ovarian, stomach, colorectal, or pancreatic cancer) that have come back or not responded to other treatments. The goal is to see if XYA02 can shrink tumors or slow their growth, and to find the best dose.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
190 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • Your cancer has come back or hasn't responded to standard treatments, and you've had at least one prior therapy (like chemotherapy or immunotherapy).
  • You need to have measurable disease on scans and a life expectancy of at least 3 months.
  • Your kidney, liver, and blood counts must be within certain limits, and you can't have had certain treatments recently (like chemotherapy or radiation within 28 days).
  • You can't have untreated or symptomatic brain metastases, serious heart/lung problems, or active infections.
  • You must be willing to provide a tumor sample from an earlier biopsy or get a new one if it's safe.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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