Testing PL54 injection for adults with PKU
Part of Brain & nervous system, Genetic & congenital, Hormones & metabolism clinical trials.
This study tests a new injection called PL54 to see if it is safe and tolerable for adults with phenylketonuria (PKU), a condition where the body cannot break down an amino acid called phenylalanine. It is designed for people with high blood phenylalanine levels and may offer a new treatment option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old.
- You have been diagnosed with PKU and have high phenylalanine levels in your blood.
- You are able to keep your diet stable from 3 days before screening until the end of the study.
- You have not used any PKU medication or injectable medicines containing PEG in the past 2 to 3 weeks.
- You have not used Pegvaliase (PALYNZIQ®) or any gene therapy for PKU before.
- You do not have serious health conditions like heart, liver, or immune system problems, and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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