Leukocyte and platelet-rich fibrin to prevent jawbone damage after tooth extraction
Part of Bones, joints & muscles, Mouth & dental clinical trials.
This study tests a special blood-derived gel called leukocyte and platelet-rich fibrin (L-PRF) to help prevent jawbone damage after tooth extraction in people who have had head or neck radiation or take bone-strengthening medications. L-PRF is made from a small amount of your blood and placed in the extraction socket to promote healing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You need to have at least one tooth that cannot be saved and needs to be removed.
- You must be able to give informed consent and attend follow-up visits over 12 months.
- If you had radiation therapy for head or neck cancer, the dose must have been at least 50 Gy.
- If you take or have taken bone-strengthening drugs like bisphosphonates or denosumab, your medical records must show this.
- You must not be taking blood thinners, immune-suppressing drugs, or other medications that slow healing.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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