Adding surgery to donepezil for Alzheimer's disease
Part of Brain & nervous system clinical trials.
This trial tests whether a surgery called lymphatic-venous anastomosis, when added to the Alzheimer's medication donepezil, is more effective than donepezil alone. It may help improve memory and thinking by clearing waste from the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age between 50 and 80 years old
- Diagnosed with Alzheimer's disease and dementia
- Score 24 or lower on a memory test (MMSE)
- A brain PET scan shows amyloid plaques (a sign of Alzheimer's)
- Not taking any Alzheimer's drugs for the past month
- In overall good health for surgery (ASA grade 1-3)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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