How trisomy 8 autoinflammatory disease progresses over time
Part of Blood & lymphatic, Infections clinical trials.
This study follows people who have trisomy 8 (an extra copy of a chromosome) that causes inflammation and mouth/genital ulcers, and their family members. Researchers want to learn how this condition changes over time, so they can better understand and treat it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are willing and able to follow the study rules.
- You are any age up to 99 and can come to the NIH (or connect remotely depending on your age and where you live).
- You let researchers store your data and leftover blood/tissue samples for future studies.
- For affected participants: You have been diagnosed with trisomy 8 mosaicism through genetic testing, OR you have inflammatory mouth or genital sores that look like trisomy 8 autoinflammatory disease.
- For unaffected biological relatives: You are a family member without the disease, can give consent, and will provide at least one blood or tissue sample.
- You do not have any medical condition or take any medication that the study doctor thinks would make it unsafe for you to take part.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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