Lemborexant for moderate sleep apnea with low arousal threshold
Treatments studied
Part of Brain & nervous system, Lungs & breathing clinical trials.
This trial tests whether a once-daily sleep medication, lemborexant, can help people with moderate obstructive sleep apnea who have a low arousal threshold (wake up easily from sleep). It aims to find the best one-month dosing schedule.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 65 years old
- You have moderate obstructive sleep apnea (15-30 events per hour on a sleep test)
- You have a low arousal threshold, meaning you wake up easily from brief pauses in breathing
- Your oxygen levels are generally above 94% during a screening visit
- You typically sleep at least 5.5 hours per night with a usual bedtime between 9 PM and 1 AM
- Your body mass index (BMI) is between 18 and 40
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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