SCAD-ALIGN: Testing antiplatelet therapy after a heart artery tear
Part of Heart & circulation clinical trials.
This trial compares different intensities of antiplatelet therapy for people who had a heart attack caused by a spontaneous tear in a heart artery (SCAD). It aims to find the best balance between preventing clots and avoiding bleeding risks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You had a recent heart attack or acute coronary syndrome
- Doctors found a suspected SCAD (spontaneous coronary artery dissection) on your angiogram
- Your doctors plan to treat the SCAD without stents or surgery (conservative management)
- You are willing to take either moderate or intensive antiplatelet medication
- You can understand the study information and give written consent
- If you could become pregnant, you agree to use effective birth control during the study (for 12 months)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial is for people who have had a spontaneous coronary artery dissection (SCAD), a tear in a heart artery. It aims to learn more about this condition and how to treat it.
This trial studies whether taking a beta-blocker and an antiplatelet (blood thinner) helps people recover after spontaneous coronary artery dissection (SCAD). It randomizes participants to treatment combinations, aiming to see which approach works best after an event affecting heart blood flow.
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This study looks for genetic (inherited) reasons some people develop SCAD, a sudden tear in a heart artery. It compares people with SCAD to people without it and may help doctors recognize risk and causes.
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