Clin2
NCT07684911Possibly a fitRecruiting

Long-term effects of TMS for depression

Depression - Major Depressive DisorderDepression BipolarDepression Unipolar

Part of Mental health clinical trials.

This study looks at how well the benefits of transcranial magnetic stimulation (TMS) last over time for people with depression that didn't get better with other treatments. It also uses brain scans to find markers that might predict who will keep doing well.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
30 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years old or older.
  • You have been diagnosed with unipolar or bipolar depression that did not improve with other treatments (treatment-resistant), and you have previously responded well to a course of TMS (your depression scores dropped by at least half).
  • You can speak and read French well enough to fill out questionnaires and follow instructions during MRI scans and TMS sessions.
  • You are willing to follow all study procedures, attend appointments for the full study period, and tell the study team about any side effects or health changes.
  • You are not at high risk for suicide, currently experiencing a psychotic episode, or have unstable medical conditions like active cancer, uncontrolled hormone problems, or untreated sleep apnea.
  • You do not have metal in your body that would make an MRI unsafe, or severe claustrophobia.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07804459Not yet recruiting· Early Phase 1
Personalized brain stimulation for depression

This study uses brain imaging to guide a noninvasive treatment called transcranial magnetic stimulation (TMS) for people with depression. It aims to see if tailoring the stimulation to each person's brain can improve symptoms.

Philadelphia, Pennsylvania
NCT07026461Recruiting· Phase 4
TMS for depression: comparing two brain stimulation methods

This trial compares two types of transcranial magnetic stimulation (TMS) to see which works better for people with depression. TMS uses magnetic pulses to stimulate brain areas involved in mood regulation.

Örebro
NCT07207239Enrolling by invitation
Brain stimulation for treatment-resistant depression

This trial is testing a type of brain stimulation therapy called theta-burst rTMS to see if it helps with depression that hasn't improved with standard treatments. It also uses brain scans to predict who might respond best.

Budapest, Pest County
NCT07043738Not yet recruiting
Comparing two ways to target brain stimulation for depression

This study tests two methods of targeting repetitive transcranial magnetic stimulation (TMS) for depression: one using brain imaging to guide the treatment, and the other using a standard scalp measurement. The goal is to see if imaging-guided TMS works better for people with treatment-resistant depression.

NCT07039370Recruiting
TMS for depression: looking for brain signals of response

This trial tests if brain scans or electrical signals can predict who will get better with TMS (transcranial magnetic stimulation) for depression. It is for people whose depression did not improve after trying two or more antidepressants.

Ankara, Ankara
NCT06572683Enrolling by invitation
Novel TMS for hard-to-treat depression

This trial tests a new type of transcranial magnetic stimulation (TMS) for people with severe depression that hasn't improved with multiple medications or therapy. It uses a different frequency pattern to target brain circuits.

Los Angeles, California

Hear when a new Depression - Major Depressive Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.