Clin2
NCT07685678Possibly a fitNot yet recruiting

Ripertamab for neuromyelitis optica spectrum disorder

Neuromyelitis Optica Spectrum Disease (NMOSD)Ripertamab

Treatments studied

Part of Brain & nervous system, Immune system & allergy clinical trials.

This trial tests a new drug called Ripertamab for people with neuromyelitis optica spectrum disorder (NMOSD), a condition that causes inflammation in the optic nerves and spinal cord. The drug aims to reduce relapses (flare-ups) of symptoms. It may be an option if you've had recent relapses despite current treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
20 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with neuromyelitis optica spectrum disorder (NMOSD).
  • You have had at least 1 relapse needing rescue treatment in the past year, or 2 relapses in the past 2 years.
  • You have not taken certain immune-suppressing drugs (like rituximab) recently, or your B-cell counts are back to normal.
  • You are willing to use effective contraception during the study and for 6 months after treatment.
  • You do not have active infections or other serious immune diseases (like rheumatoid arthritis).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07388810Not yet recruiting
Ripertamab for frequent relapses in nephrotic syndrome

This trial tests a new medicine called ripertamab for children and young adults with nephrotic syndrome that keeps coming back or requires steroids. The goal is to see if it helps prevent relapses with fewer side effects.

Hangzhou, Zhejiang
NCT07592754Not yet recruiting· Early Phase 1
KSVCBD injection for neuromyelitis optica

This trial tests whether an investigational drug called KSVCBD can safely reduce relapses in people with neuromyelitis optica spectrum disorder (NMOSD). If you have had at least one relapse in the past year and meet other criteria, you may be able to join.

Beijing, Beijing Municipality
NCT06858722Not yet recruiting· Phase 3
Ripertamab for chronic inflammatory demyelinating polyneuropathy

This trial tests an investigational drug called Ripertamab for people with chronic inflammatory demyelinating polyneuropathy (CIDP), a nerve condition causing weakness and numbness. The goal is to see if the drug can improve symptoms compared to no additional treatment.

NCT07372807Not yet recruiting· Phase 1/Phase 2
Ripertamab for generalized myasthenia gravis

This study tests a new medicine called ripertamab for people with generalized myasthenia gravis (gMG), a condition that causes muscle weakness. The medicine aims to reduce the immune system's attack on muscles, which may help improve daily activities and quality of life.

NCT07182409Not yet recruiting
Monoclonal antibody for acute neuromyelitis optica attacks

This trial tests a new antibody-based medicine to help people recover from an acute attack of neuromyelitis optica spectrum disorder (NMOSD), a condition that causes inflammation in the eyes and spinal cord. If you are having a recent flare-up and are already getting or planning to get steroid treatment, this study might offer an additional option to reduce damage and speed recovery.

NCT07557420Recruiting· Phase 3
Ravulizumab for Neuromyelitis Optica Spectrum Disorder in Chinese Adults

This study tests a new medicine called ravulizumab (an infusion) to reduce relapses in people with neuromyelitis optica spectrum disorder (NMOSD), a rare condition affecting the optic nerve and spinal cord. The trial is specifically enrolling adults in China who have had recent disease activity.

Beijing

Hear when a new Neuromyelitis Optica Spectrum Disease (NMOSD) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.