Pregnenolone for cannabis use and depression
Treatments studied
Part of Mental health clinical trials.
This study tests a natural supplement called pregnenolone to see if it helps reduce cannabis use and improve depression. Participants receive the study drug or a placebo and are monitored over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 50 years old.
- You must have a diagnosis of cannabis use disorder and major depressive disorder (clinical depression).
- You must be using cannabis at least 4 days per week in the past month.
- You must be willing to reduce your cannabis use.
- You cannot have other substance use disorders (besides nicotine), or a history of psychotic or bipolar disorders.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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