Heart failure treatment with diabetes drug and probiotics
Part of Heart & circulation clinical trials.
This study tests whether combining a diabetes medication (SGLT-2 inhibitor) with probiotics can improve heart failure symptoms in older adults. It aims to see if this combination helps the heart work better and reduces symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 60 years or older.
- You have heart failure with preserved ejection fraction (your heart pumps normally but doesn't fill properly).
- You have symptoms like shortness of breath or fatigue (NYHA class II or III).
- You have not taken SGLT-2 inhibitors (like dapagliflozin or empagliflozin) in the last 6 months.
- You have not taken probiotics in the last 3 months.
- You are willing to take the study medication and probiotics for the duration of the trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether a type of diabetes medicine called SGLT2 inhibitors (also known as flozins) can help protect the heart and kidneys in people with both heart failure with preserved pumping function and moderate chronic kidney disease, with or without diabetes.
This trial studies whether two medicines—an SGLT2 inhibitor and potassium nitrate—can improve symptoms and heart function in people with heart failure with preserved ejection fraction (HFpEF). It focuses on people who still have signs of “stiff” or high filling pressure in the heart despite a normal-ish ejection fraction.
This study tests whether a medication called empagliflozin (a diabetes drug) can improve heart function in older adults with high blood pressure and obesity who are at risk for heart failure but do not have it yet. You would take the pill daily and have heart ultrasounds to check your heart's health.
This trial tests if a medication can prevent heart failure in older adults who are at risk. It is for people aged 65 or older who are having certain heart procedures or a major surgery.
This trial tests if a medicine (SGLT2 inhibitor) given to people with high blood pressure and early signs of heart stress can help prevent heart failure. You may join if your blood pressure is controlled but tests show your heart is beginning to struggle.
This clinical trial looks at whether adding a special diet supplement (ketones) to an SGLT2 inhibitor diabetes drug improves heart function and symptoms in people who have both type 2 diabetes and heart failure with a weakened heart muscle.
Hear when a new Heart Failure, Preserved Ejection Fraction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.