Regenerative medicine for joint looseness and instability
Treatments studied
Part of Blood & lymphatic, Bones, joints & muscles, Genetic & congenital, Heart & circulation, Injuries & trauma, Pain, Skin clinical trials.
This trial tests if regenerative injections (like dextrose, PRP, or doxycycline) can help people with loose joints that cause pain and have not improved with physical therapy. It also offers an alternative treatment with hyaluronic acid for those who don't respond well to the regenerative options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a diagnosis of joint hypermobility (like Ehlers-Danlos syndrome) or joint looseness after an injury, confirmed by a doctor.
- You have had pain in the affected joint for at least 3 months, with a pain level of 4 or higher on a 0–10 scale.
- You have tried at least 6 weeks of physical therapy for the painful joint without enough relief.
- You are not using NSAIDs (like ibuprofen) and can avoid them during treatment.
- You are willing to follow study procedures and attend follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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