Collagenase injection for managing contractures
Part of Bones, joints & muscles clinical trials.
This trial tests whether a collagenase injection can help loosen tight tendons (contractures) caused by a stroke, brain injury, or spinal cord injury. If you have had a contracture for at least 6 months and are otherwise stable, this treatment might improve your range of motion.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a stroke, brain injury, or spinal cord injury at least 6 months ago and your condition is stable
- You have a tight tendon (contracture) diagnosed by a doctor
- You are not allergic to collagenase (XIAFLEX)
- You have not had botox in the area for at least 4 months, or phenol injections for at least 9 months
- You are not currently taking blood thinners (other than low-dose aspirin) and do not have a bleeding disorder
- You do not have a connective tissue disorder like Ehlers-Danlos syndrome
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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