Collagenase injection for tightening after nerve injury
Part of Bones, joints & muscles clinical trials.
This study tests a medicine called collagenase (Xiaflex) that is injected into tight tendons to help release them. It's for people who have had a stroke, brain injury, or spinal cord injury and now have a tendon contracture, which can limit movement.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a stroke, brain injury, or spinal cord injury more than 6 months ago.
- You have a tendon contracture (a tightened tendon that limits joint movement).
- Your muscle relaxant medications (like baclofen) are stable, not being adjusted.
- You haven't had Botox injections in the last 4 months or phenol injections in the last 9 months.
- You are not taking blood thinners (except low-dose aspirin).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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