Clinical trials
Contracture clinical trials
Below are recruiting contracture clinical trials, each written for real people, not researchers. We’re tracking 22 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04122313Recruiting
Radiation after surgery for Dupuytren’s hand contracture
This trial looks at using radiation after contracture-release surgery for people with Dupuytren’s disease. It may help prevent the hand tightening from coming back and improve hand function.
Minneapolis, MinnesotaAges 18 years+ - NCT05945329Recruiting
New scar-wrap to treat painful tightness after breast implants
This trial tests a medical mesh/scaffold (GalaFLEX LITE™) used during revision surgery to help treat capsular contracture, where scar tissue tightens around a breast implant. It may improve comfort and the appearance of the breast after implant augmentation problems.
Scottsdale, ArizonaAges 22–70 - NCT05440240RecruitingPhase 4
Needling and possibly steroid shot for Dupuytren’s hand tightness
This trial tests a minimally invasive procedure that uses a needle to release tight tissue in the hand, and may include a steroid injection. It aims to improve hand finger straightening for people with Dupuytren’s contracture.
SilkeborgAges 45–99 - NCT07339397Recruiting
Joint stiffness in ICU patients on breathing machines
This trial studies how common joint stiffness becomes in ICU patients who are on a breathing machine and cannot move for at least 7 days. It may help doctors better prevent and treat this problem.
Elâzığ, ElaziğAges 18 years+ - NCT05300893Recruiting
Night splinting after a minimally invasive hand release
This trial checks whether wearing a night splint after a specific procedure for Dupuytren’s contracture helps keep your fingers straighter. It’s meant to reduce the chance of the hand contracting again during recovery.
Falun, Dalarna CountyAges 18 years+ - NCT06330545Recruiting
Radiation for Dupuytren's after non-surgical release
This study tests if a short course of radiation therapy can help prevent Dupuytren's contracture from coming back after a non-surgical release (like an injection). It may be an option for people whose finger is already bent and cannot touch the table.
Lebanon, New HampshireAges 45 years+ - NCT06788847Recruiting
Ultrasound-guided needle knife for Dupuytren's contracture
This trial tests a less invasive procedure using a needle-knife guided by ultrasound to treat Dupuytren's contracture, which causes fingers to curl. It may be an option if you haven't had prior treatment on the same hand and are in otherwise good health.
Al Mansurah, Dakahlia GovernorateAges 18 years+ - NCT07640425RecruitingPhase 1/Phase 2
Testing a new collagenase injection for Dupuytren's contracture
This study tests whether a new injectable enzyme called CNT201 can safely and effectively treat Dupuytren's contracture—a condition where fingers curl and can't straighten. The injection aims to break down the thick tissue cords causing the problem, without surgery.
Kippa-Ring, QueenslandAges 18–75 - NCT06377085Enrolling by invitationPhase 1
Testing an old drug for tight muscles in kids with cerebral palsy
This trial tests a drug called 5-Azacytidine, which is being used in a new way—to help loosen tight muscles (contractures) in children with cerebral palsy. It aims to see if it can reduce the need for surgery.
San Diego, CaliforniaAges 2–18 - NCT07460297Enrolling by invitation
Antibiotic and iodine for infection prevention in breast reconstruction
This trial tests if a combination of a pseudomonas bacteria injection and an iodine solution can help prevent infections in women having immediate breast reconstruction with implants after mastectomy or breast-conserving surgery.
Shenyang, LiaoningAges 18 years+ - NCT07454356Recruiting
Device to help knee bending after replacement
This study tests a non-surgical device called Knee Flexionater to help people who have limited knee bending after total knee replacement. The goal is to improve knee motion and avoid a second surgery.
Houston, TexasAges 40 years+ - NCT07419971Enrolling by invitation
Factors behind breast implant hardening after reconstruction
This study looks at why some women develop hard scar tissue around breast implants after cancer surgery. It aims to find the causes and ways to prevent it.
Chengdu, SichuanAges 18–80 - NCT07248475Recruiting
Battle rope training for elbow pain and stiffness after injury
This study tests whether battle rope exercises can help children ages 8–15 with elbow stiffness and pain after an injury. It aims to improve movement and reduce discomfort.
Lahore, Punjab ProvinceAges 8–15 - NCT06857435Recruiting
Fat graft for scar release: a new approach
This trial tests if using your own fat cells during scar surgery helps heal better. If you need surgery to release a tight scar, you may be able to receive a fat graft from your own body.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06857448Recruiting
Fat grafting for recent wounds and burns
This trial tests whether using your own fat cells can help heal wounds or burns that need surgery. It is for adults who have had a fasciotomy, full-thickness skin loss, or burns, and are willing to receive a fat graft.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04342546Recruiting
Radiation skin side-effect test after mastectomy with implant
This trial looks at a test meant to predict how likely you are to develop side effects from radiation to the chest wall after mastectomy. It is designed for people getting immediate breast reconstruction using an implant, so treatment planning may be safer and more personalized.
DijonAges 18 years+ - NCT05506228Recruiting
Muscle biopsy during surgery study in brain injury conditions
This study looks at how muscles are affected in children and teens with cerebral palsy or an acquired brain injury. Researchers take a small muscle tissue sample during surgery that you were already having for medical reasons, to better understand muscle changes.
StockholmAges 2–18 - NCT05518565Recruiting
Study muscle changes in people with cerebral palsy
This study looks at how muscles work in the body in people with cerebral palsy or an acquired brain injury. It may help researchers understand muscle structure and changes over time, which could guide future treatments.
StockholmAges 2–18 - NCT06308380Recruiting
Rehab for tight leg muscles and ankle pain
This trial tests a rehabilitation program for people with tight back leg muscles that cause ankle pain, trouble walking, or daily activity limits. It may help if you have chronic ankle pain or a condition like clubfoot.
Granollers, BarcelonaAges 20–90 - NCT06574737Recruiting
Can muscle signals predict arm recovery after stroke?
This study tests whether a simple muscle signal test (called surface EMG) can predict how well your arm will recover after a stroke. It involves placing small stickers on your skin to measure muscle activity while you try to move your affected arm.
Bandung, West JavaAges 18 years+ - NCT06912061Recruiting
New needle technique for Achilles tendon lengthening in kids
This study tests a new needle-based method to lengthen a tight Achilles tendon in children, which can help with toe walking or foot pain. The goal is to see if it works well and is safe.
DrammenAges 5–16 - NCT03155854Recruiting
Surgery to prevent scarring in trigger finger
This study looks at whether doing a limited surgery in advance can improve outcomes and reduce scarring for people with trigger finger who also have a specific palm cord condition. It may help you heal better if you’ve already tried non-surgical treatment or chose surgery.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for contracture?
- Yes. Clin2 currently lists 22 recruiting contracture studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a contracture trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a contracture trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.