Brain-computer interface for speech in locked-in syndrome
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests a brain implant that may help people with locked-in syndrome communicate by translating brain signals into words or letters on a screen. It aims to see if the device is safe and works well enough to be used in daily life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have locked-in syndrome due to a stroke in the lower part of the brain or ALS (a nerve disease), which causes severe speech problems.
- Your health is stable, especially your breathing, and you can read a screen by moving your eyes.
- You can undergo brain scans (MRI, CT) and can have the implant surgery.
- You are able to do a simple brain-computer test using MEG (a brain scanner).
- A psychiatrist has confirmed that you can handle the long training needed for the implant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
This study tests a brain-computer interface (BCI) that uses augmented reality glasses to help people with late-stage ALS communicate. You wear a headset that reads your brain signals and lets you select words or phrases on a screen, giving you a new way to talk to others.
This study tests how well people with ALS, spinal cord injury, or healthy volunteers can use a brain-computer interface (BCI). The goal is to learn how to measure what the device can do, which may help people with severe communication or movement limitations.
This study tests a brain-computer interface to help people with severe paralysis communicate by decoding attempted speech or movements. It may offer a new way to interact with devices using only brain signals.
This study tests a surgically implanted brain-computer interface (BCI)—a device that reads signals directly from your brain to help control a computer cursor or robotic arm. It's designed for people with ALS whose arms are paralyzed and who haven't responded to standard treatments.
This trial uses a special brain-mapping test called high-density ECoG to study how people who have lost speech due to stroke, brain tumor, or ALS can be helped by reading brain signals when they imagine speaking. It may lead to new devices that let people with severe speech problems communicate using only their thoughts.
Hear when a new Locked in Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.