Brain signal study for speech recovery after stroke or injury
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial uses a special brain-mapping test called high-density ECoG to study how people who have lost speech due to stroke, brain tumor, or ALS can be helped by reading brain signals when they imagine speaking. It may lead to new devices that let people with severe speech problems communicate using only their thoughts.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 20 and 80 years old.
- You can understand and agree to take part in the study.
- Your speech problems have lasted more than 12 months and have not improved much after 3-6 months of therapy.
- You have severe speech difficulty (such as not being able to speak clearly or understandably) due to a stroke, brain tumor, ALS, or locked-in syndrome.
- You can still understand language fairly well (hearing and reading comprehension at least 80% of normal).
- You do not have a metal implant or other condition that would make an MRI or brain surgery unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new brain implant (CortiCom) that may help people who are locked-in or nearly locked-in communicate again. It involves surgery to place the device in the brain and requires a caregiver and commitment to follow-up visits.
This study uses gentle electrical stimulation on the brain during awake surgery to understand how language works. It's for people having brain tumor removal or epilepsy monitoring who can speak English and do not have serious speech or thinking problems.
This trial tests a brain implant that may help people with locked-in syndrome communicate by translating brain signals into words or letters on a screen. It aims to see if the device is safe and works well enough to be used in daily life.
This study looks at brain signals recorded during surgery to better understand how the brain names pictures. It may help surgeons protect language areas during brain tumor removal.
This study looks at brain activity during speech tasks to better understand why some people with aphasia have trouble coordinating speech. It compares people with long-term (chronic) left-stroke aphasia to healthy volunteers, using EEG and MRI.
This study uses brain scans to understand how the brain controls speech in people who have had a cerebellar stroke. It is looking for both stroke survivors and healthy volunteers to compare.
Hear when a new Aphasia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.