Crisugabalin for nerve pain in NMOSD
Treatments studied
Part of Brain & nervous system, Eyes & vision, Immune system & allergy, Pain clinical trials.
This study tests whether a new medication called Crisugabalin can reduce nerve pain in people with NMOSD. It's a 4-week trial where you could receive the study drug or a placebo (a dummy pill) — neither you nor your doctor will know which one you get.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have NMOSD (neuromyelitis optica spectrum disorder) that tested positive for AQP4 antibodies.
- You have nerve pain from NMOSD that scores at least 4 on a 10-point pain scale, and your pain medicines have not changed in the last month.
- You have not already taken this study drug (Crisugabalin) before.
- You do not have severe liver or kidney problems, are not pregnant or breastfeeding, and have not tried high doses of similar nerve pain drugs (like pregabalin or gabapentin) without success.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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