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NCT07699770Possibly a fitNot yet recruiting

Crisugabalin for nerve pain in NMOSD

Neuromyelitis Optica Spectrum Disorders (NMOSD)Neuropathic Pain

Treatments studied

Part of Brain & nervous system, Eyes & vision, Immune system & allergy, Pain clinical trials.

This study tests an investigational drug called crisugabalin, which may help reduce nerve pain caused by NMOSD. If you join, you will receive either the drug or a placebo (a pill with no active medicine) to see how well it works.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
110 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old.
  • You must have a confirmed NMOSD diagnosis and be positive for the AQP4 antibody.
  • You must have nerve pain (neuropathic pain) related to your NMOSD that has been stable for at least a month.
  • Your average pain score on a 0-10 scale should be at least 4.
  • You must not have had severe kidney or liver problems, and must not be pregnant or planning pregnancy.
  • You must not have tried certain other nerve pain medications (like high doses of pregabalin or gabapentin) without success.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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