High-protein diet and strength training with tirzepatide (HUSTLE)
Part of Hormones & metabolism clinical trials.
This study tests whether adding a high-protein diet and strength training helps people taking tirzepatide (Mounjaro or Zepbound) lose fat while keeping muscle. You would follow a special diet plan and do supervised exercise twice a week for 6 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age between 30 and 60 years old
- BMI between 27 and 37
- You are about to start or just started tirzepatide (Zepbound or Mounjaro) within the last 4 weeks with little to no weight loss yet
- Willing to follow a high-protein diet and do strength training twice a week
- Able to travel to New York City for study visits and have an MRI scan
- No major health problems like diabetes, serious kidney or liver disease, unstable heart disease, or an eating disorder
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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