Ketamine and Talk Therapy for Tough Depression
Part of Mental health clinical trials.
This trial tests whether a combination of ketamine (given through an IV) and talk therapy can help people with depression that hasn't responded to other treatments. If you have tried multiple antidepressants and therapy without success, this study may offer a new option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have depression that hasn't gotten better after trying at least two antidepressants and one type of talk therapy.
- You currently have significant depression symptoms (like low mood, loss of interest, etc.).
- You do not have a current problem with drugs or alcohol, and can stop drinking alcohol for 24 hours before and after treatment.
- You are not currently at risk of harming yourself or others.
- You are not pregnant, breastfeeding, or undergoing IVF treatment, and you have a healthy bladder and liver.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether ketamine, given with talk therapy, can help people whose depression hasn't improved with at least two antidepressants. It aims to see if this combination can reduce depression symptoms.
This study compares ketamine alone to ketamine combined with psychotherapy for treating depression. It may help if you have moderate to severe depression and want to see if adding talk therapy improves results.
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