Ketamine combined with ECT for hard-to-treat depression
Treatments studied
Part of Mental health clinical trials.
This trial tests whether adding ketamine to electroconvulsive therapy (ECT) works better than ECT alone for people with depression that hasn't improved with at least two different antidepressants. It may offer a new option for those who have not found relief from standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 70 years old.
- You must have major depressive disorder that has not improved after trying at least two different antidepressants.
- You must be able to undergo ECT and give informed consent for the procedures.
- You cannot have certain heart, brain, or other medical conditions that make ECT or ketamine unsafe.
- You cannot have a history of alcohol or drug use disorder in the past year.
- You cannot be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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