Can manidipine help reverse aortic valve calcification?
Part of Heart & circulation clinical trials.
This trial tests whether the blood pressure medication manidipine can slow or reverse calcium buildup in the heart's aortic valve. Researchers are looking for older adults with mild-to-moderate aortic valve narrowing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 60 years or older.
- You have a condition called calcific aortic valve disease with mild to moderate narrowing (calcium buildup in the valve).
- At a recent heart ultrasound, the pressure across your valve was between 10 and 30 mmHg and the valve area was between 1.2 and 2.0 square centimeters.
- A special CT scan within the last month showed a calcium score of at least 200 in your aortic valve.
- You are willing to follow the study plan and give written permission to participate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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