Manidipine study for aortic valve calcium buildup
Part of Heart & circulation clinical trials.
This trial tests an experimental medication to see if it can reduce calcium buildup in the aortic valve, potentially slowing the progression of aortic stenosis. Participants receive the study drug and are monitored with imaging over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 60 or older.
- You have mild to moderate aortic valve stenosis (a narrowed heart valve) confirmed by an ultrasound of the heart.
- A heart CT scan shows calcium buildup on your aortic valve (score of 200 or more).
- You do not have significant disease of the other heart valves (mitral or tricuspid).
- You have not had aortic valve surgery, pancreatitis, cancer, or substance abuse in the past.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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