How blood pressure hormones change in septic shock
Part of Infections clinical trials.
This study looks at how a hormone system that controls blood pressure acts in people with septic shock (a severe infection causing low blood pressure). It compares patients with septic shock, sepsis without shock, cardiogenic shock, and healthy people to find differences that might lead to better treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- If you have septic shock: you have an infection, your blood pressure stays low despite fluids and you need medication to keep it up, and your blood lactate (a sign of poor oxygen) is high.
- If you have sepsis without shock: you have an infection, your blood pressure is okay, and your organ function score (SOFA) has increased by at least 2 points.
- If you have cardiogenic shock: you have a recent heart problem (like a heart attack), low blood pressure, weak heart pumping, and high lactate levels.
- If you are a healthy volunteer: you have no active or long-term diseases, are not on long-term medications, have not had surgery or taken medications in the last month, are not pregnant, and do not smoke.
- You must not have been in the ICU for more than 48 hours, be under legal guardianship or custody, or receive state medical aid.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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