Testing zastaprazan to prevent stomach bleeding after stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a new medicine, zastaprazan, to see if it can prevent stomach or intestinal bleeding in people who have had a stroke or mini-stroke and are taking blood thinners or anti-clotting drugs. It might help protect your stomach while you're on these medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years or older
- You had a mini-stroke or ischemic stroke within the last 6 months
- You are starting or already taking one of these treatments for at least 3 weeks: two antiplatelet drugs together (like aspirin and clopidogrel) or a blood thinner (like apixaban or warfarin)
- You do not have a serious liver condition, active bleeding, or very low platelets
- You are not pregnant or planning pregnancy, and use reliable birth control if needed
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial is testing whether combining aspirin with either cilostazol or clopidogrel is more effective at preventing another stroke after a minor stroke or TIA. It is for people who had their first mild stroke or TIA and started a blood thinner within 24 hours.
This trial tests whether giving a clot-dissolving medicine (alteplase or tenecteplase) is safe and effective for people who have had a stroke and are taking a blood thinner (DOAC) like apixaban or rivaroxaban. It aims to see if this treatment can still be given within a few hours of the stroke.
This trial tests whether taking aspirin along with either ticagrelor or cilostazol helps prevent another stroke in people who have had a mild stroke or transient ischemic attack (mini-stroke). You must start treatment within 24 hours of your first symptoms.
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