Vascular graft for artery bypass or replacement
Part of Heart & circulation clinical trials.
This trial tests a new biological graft to replace or bypass damaged arteries in the legs or abdomen. It may be an option if you need surgery to improve blood flow and don't have a healthy vein available for the repair.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You need surgery to bypass or replace an artery below the kidneys, such as for poor circulation, infection, injury, or a burst artery.
- If you have poor leg circulation, your symptoms must be severe (Rutherford stage 3–6), your ankle-brachial index (a measure of blood pressure in your ankle) is 0.6 or less, and you have at least one open artery below the knee down to your ankle.
- You must not have a healthy, full-length great saphenous vein (the main leg vein used for bypass) available for the surgery.
- You are able to give written consent and attend all follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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