NAC before stem cell transplant to improve platelet recovery in aplastic anemia
Treatments studied
Part of Blood & lymphatic clinical trials.
This study tests whether taking an antioxidant called NAC before a half-matched stem cell transplant helps platelets (the cells that help blood clot) recover faster in people with aplastic anemia. If you qualify, you may get NAC or a placebo, and the trial will see if it improves your recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have aplastic anemia and are scheduled for your first half-matched (haploidentical) stem cell transplant.
- You must be between 14 and 50 years old.
- You have no other major health problems that would make a transplant risky.
- You do not have antibodies against your donor's HLA (a protein marker).
- You cannot be allergic to NAC (the study drug) or have a history of bronchial asthma.
- You cannot be pregnant, breastfeeding, or have active stomach or digestive issues.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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