Clin2
NCT07737613Possibly a fitNot yet recruiting

Estrogen's effect on brain activity during fear learning

PTSD and Trauma-related SymptomsCognitive Decline in Older AdultsPost Menopausal Women

Treatments studied

Part of Mental health clinical trials.

This study looks at how a single dose of estradiol (a natural estrogen) affects brain activity during a fear-learning task in post-menopausal women. It may help us understand how estrogen influences emotional memory and anxiety.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
30 people
Ages
60 years and older
Study type
Interventional

Who can take part

  • You are post-menopausal (no periods for at least a year).
  • You have normal or corrected vision (glasses/contacts are fine).
  • You speak English and have not changed your regular medications in the last 3 months.
  • You are not taking hormone therapy that contains synthetic estrogen.
  • You have no metal in your body that can't be removed, and you are not claustrophobic.
  • You have no history of stroke, blood clots, migraines with aura, or certain cancers.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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