Clin2
NCT07739186Possibly a fitNot yet recruiting

First-line treatment combination for advanced non-squamous lung cancer

Non-squamous Non-small Cell Lung Cancer

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new combination of drugs (BL-B01D1 plus a bispecific antibody) against the current standard chemotherapy and immunotherapy. It aims to see if the new combination works better for people with advanced non-squamous non-small cell lung cancer who haven't had treatment before.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
120 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have locally advanced or metastatic non-squamous non-small cell lung cancer
  • You have not received any prior systemic treatment for your lung cancer
  • You are physically active (ECOG score 0 or 1) and expected to live at least 3 months
  • You can provide a tissue sample from your tumor
  • Your kidney, liver, and heart functions are adequate

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07178795Recruiting· Phase 3
New drug vs standard care for HER2-mutant lung cancer

This study is testing a new drug (BL-M07D1) compared to a standard combination of pembrolizumab and chemotherapy for people with a specific type of advanced lung cancer (non-squamous NSCLC) that has a HER2 mutation and has not been treated before. The goal is to see which treatment works better.

Guangzhou, Guangdong
NCT07383116Not yet recruiting· Phase 3
New combination for advanced non-squamous lung cancer

This trial tests a new drug combination for people with advanced non-squamous non-small cell lung cancer who have not had treatment before. It compares the new drug with a standard immunotherapy, both given with chemotherapy, to see which is more effective.

Shanghai
NCT07264816Recruiting· Phase 2
Study of BL-M07D1 and Pembrolizumab for HER2+ Lung Cancer

This study tests a new drug combination, BL-M07D1 plus pembrolizumab (an immunotherapy), for people with a certain type of advanced lung cancer that has high levels of HER2 protein. The goal is to see if the combination is safe and effective for people who have not been treated with HER2-targeting drugs before.

Wuhan, Hubei
NCT07739199Not yet recruiting· Phase 2/Phase 3
New drug combination for advanced squamous lung cancer

This trial compares a new combination of drugs (one that targets cancer cells and another that boosts the immune system) against a standard chemotherapy plus immune therapy combination. The goal is to see if the new approach works better as a first treatment for advanced squamous lung cancer.

Guangzhou, Guangdong
NCT06475300Recruiting· Phase 2
BL-B01D1 plus immunotherapy for advanced lung and throat cancers

This trial tests a new combination treatment (BL-B01D1 plus a PD-1 inhibitor) for people with advanced lung cancer or nasopharyngeal cancer. It aims to see if the combination is safe and effective for patients whose cancer has not responded to earlier treatments.

Guangzhou, Guangdong
NCT07662395Recruiting· Phase 2/Phase 3
New drug plus chemo for advanced squamous lung cancer

This trial tests a new drug (SCTB41) combined with chemotherapy for people with advanced squamous non-small cell lung cancer who have not had any prior treatment. It aims to see if this combination works better than standard therapy.

Guangzhou, Guangdong

Hear when a new Non-squamous Non-small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.