New pill compared to standard treatment for PNH
Treatments studied
Part of Blood & lymphatic clinical trials.
This trial is testing a new pill (FXS6837) compared to the standard IV medicine eculizumab for people with PNH. The study lasts 24 weeks and aims to see if the new pill works better or as well and has fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years old or older.
- Your weight must be at least 40 kg (about 88 pounds).
- You must have a confirmed diagnosis of PNH, a rare blood disorder that destroys red blood cells.
- You must not have taken any complement inhibitor medicines before (like eculizumab).
- You must have signs of active PNH, such as low hemoglobin (anemia) or high LDH (a marker of red blood cell breakdown), or have needed blood transfusions recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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