Medicine combo for sedation in ICU patients
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests a combination of two medicines, dexmedetomidine and esketamine, to help keep ICU patients calm and comfortable while on a breathing machine. The goal is to see if this combination works well for sedation and pain relief.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are in the ICU on a breathing machine (either a tube in your throat or a mask) that you will need for at least 24 hours.
- Your ICU doctor has decided you need medicine to keep you calm and comfortable.
- You are not pregnant or breastfeeding.
- You do not have a history of certain brain or nerve conditions like schizophrenia, epilepsy, Parkinson's, or myasthenia gravis.
- You do not have severe heart, liver, or kidney problems that would make this study unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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