Sound wave device to open blood-brain barrier for brain tumors
Part of Brain & nervous system, Cancer clinical trials.
This trial tests a device that uses microbubbles and sound waves (sonication) to open the blood-brain barrier so that cancer drugs can better reach brain tumors. It is for people with recurrent high-grade glioma or brain metastases that are not candidates for immediate surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Your tumor is a recurrent high-grade glioma or a brain metastasis, and it is at least 25-30 mm in size
- Surgery is not the first planned treatment, but the tumor is still operable and in a safe location (not near critical brain areas)
- You have stable blood pressure (systolic 180 or less, diastolic 100 or less) and normal blood clotting levels
- You can stop blood-thinning medications for the required time before the procedure
- You are willing to have partial head shaving and sit still during the procedure
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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